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  1. While preeclampsia (PE) is a leading cause of pregnancy-related morbidity/mortality, its underlying mechanisms are not fully understood. DNA methylation (DNAm) is a dynamic regulator of gene expression that ma...

    Authors: Shuwei Liu, Haoyi Fu, Mitali Ray, Lacey W. Heinsberg, Yvette P. Conley, Cindy M. Anderson, Carl A. Hubel, James M. Roberts, Arun Jeyabalan, Daniel E. Weeks and Mandy J. Schmella
    Citation: Epigenetics Communications 2023 3:1
  2. The Illumina EPIC array is widely used for high-throughput profiling of DNA cytosine modifications in human samples, covering more than 850,000 modification sites across various genomic features. The applicati...

    Authors: Zhou Zhang, Chang Zeng and Wei Zhang
    Citation: Epigenetics Communications 2022 2:7
  3. Distinct cell types can be identified by their DNA methylation patterns. Much research over the last decade has focused on DNA methylation changes in cancer or the use of cell-free circulating DNA in plasma to...

    Authors: M. J. Dunnet, O. J. Ortega-Recalde, S. A. Waters, R. J. Weeks, I. M. Morison and T. A. Hore
    Citation: Epigenetics Communications 2022 2:5
  4. Carcinogens in cigarette smoke may cause aberrant epigenomic changes. The hypomethylation of long interspersed nucleotide element-1 (LINE-1) in colorectal carcinoma has been associated with genomic instability...

    Authors: Junko Kishikawa, Tomotaka Ugai, Kenji Fujiyoshi, Yang Chen, Koichiro Haruki, Li Liu, Kota Arima, Naohiko Akimoto, Tsuyoshi Hamada, Kentaro Inamura, Keisuke Kosumi, Tyler S. Twombly, Shanshan Shi, Mai Chan Lau, Chunxia Du, Peilong Li…
    Citation: Epigenetics Communications 2022 2:4
  5. Advanced maternal age is currently a term defined by chronological age. However, a group of biomarkers known as epigenetic clocks, which can predict morbidity and mortality, has been used to estimate measures ...

    Authors: Elise N. Erickson, Anna K. Knight, Alicia K. Smith and Leslie Myatt
    Citation: Epigenetics Communications 2022 2:3
  6. Renal cell carcinoma (RCC) is the fourteenth most common cancer worldwide, accounting for approximately 4% of all cancers. More than 70% of RCC are clear cell RCC (ccRCC). To date, no reliable biomarkers for t...

    Authors: Hideki Ohmomo, Shohei Komaki, Yoichi Sutoh, Tsuyoshi Hachiya, Kanako Ono, Eri Arai, Hiroyuki Fujimoto, Teruhiko Yoshida, Yae Kanai, Koichi Asahi, Makoto Sasaki and Atsushi Shimizu
    Citation: Epigenetics Communications 2022 2:2
  7. Aging populations in Africa face a growing burden of non-communicable diseases (NCDs), contextualized in broad external exposome and weak health systems. These could accelerate aging and shorten lifespan. DNA ...

    Authors: Dafne Sanchez, Ayoung Jeong, Clemence Essé, Fidèle K. Bassa, Siaka Koné, Félix Acka, Véronique Laubhouet-Koffi, Dinard Kouassi, Jürg Utzinger, Eliézer K. N’Goran, Bassirou Bonfoh, Medea Imboden, John W. Holloway and Ikenna C. Eze
    Citation: Epigenetics Communications 2022 2:1
  8. The vast majority of eukaryotic transcription occurs in bursts during discrete periods of promoter activity, separated by periods of deep repression and inactivity. Elucidating the factors responsible for trig...

    Authors: William F. Beckman, Miguel Ángel Lermo Jiménez and Pernette J. Verschure
    Citation: Epigenetics Communications 2021 1:6
  9. Despite the known role of mitosis in colorectal cancer, previous associations of long-term aspirin use with suppressed cancer-related epigenetic aging did not involve epigenetic mitotic clocks. We investigated...

    Authors: Jamaji C. Nwanaji-Enwerem, Chijioke Nze and Andres Cardenas
    Citation: Epigenetics Communications 2021 1:5
  10. Following aneurysmal subarachnoid hemorrhage (aSAH), the brain is susceptible to ferroptosis, a type of iron-dependent cell death. Therapeutic intervention targeting the iron homeostasis pathway shows promise ...

    Authors: Lacey W. Heinsberg, Daniel E. Weeks, Sheila A. Alexander, Ryan L. Minster, Paula R. Sherwood, Samuel M. Poloyac, Sandra Deslouches, Elizabeth A. Crago and Yvette P. Conley
    Citation: Epigenetics Communications 2021 1:4
  11. Delayed cerebral ischemia (DCI) is a common secondary complication and an important cause of disability and mortality among patients who survive aneurysmal subarachnoid hemorrhage (aSAH). Knowledge on DCI path...

    Authors: Dongjing Liu, Annie I. Arockiaraj, John R. Shaffer, Samuel M. Poloyac, Paula R. Sherwood, Sheila A. Alexander, Elizabeth A. Crago, Daniel E. Weeks and Yvette P. Conley
    Citation: Epigenetics Communications 2021 1:3
  12. Biological aging may occur at different rates than chronological aging due to genetic, social, and environmental factors. DNA methylation (DNAm) age is thought to be a reliable measure of accelerated biologica...

    Authors: Lacey W. Heinsberg, Dongjing Liu, John R. Shaffer, Daniel E. Weeks and Yvette P. Conley
    Citation: Epigenetics Communications 2021 1:2