Epigenetics Communications

New thematic series: Multiscale chromatin dynamics

New Content Item We are proud to announce a new cross-journal thematic series between Epigenetics Communications and Clinical Epigenetics, guest edited by Pernette Verschure and Wim Vanden Berghe. The last few years have seen a wealth of knowledge on the role of epigenetic gene regulation in (patho-)physiological processes. New insights relate to the highly dynamic nature of epigenetic systems. Epigenetic regulatory proteins are in constant motion in the nucleus, exchanging between chromatin-bound and unbound states. In addition, various layers of chromatin folding show defined dynamics. The causal relationship between these dynamics of chromatin and nuclear organization with gene activity and silencing is still an open question of great importance. Find out more about the scope here.

DNA Day 2021 Blog: DNA and its (journal) children

New Content Item Please check out a special DNA Day blog by the University of Bath's Vanessa Tse, recognizing the important breakthroughs we celebrate every April 25th and looking at Epigenetics Communications and its companion journal Clinical Epigenetics.

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Epigenetics Communications is accepting submissions and will publish its first articles soon.

Editorial Policy Regarding Submissions describing “Negative Outcome Studies”

Provided that the methodology is consistent and sound, and the research question brings added value to the field, we warmly welcome ‘negative results’ studies. Manuscripts to be considered include, but are not limited to, descriptions of:

(failed) attempts to reproduce previously published data
irreproducible data between two (collaborating) laboratories
failed, but technically solid, attempts to prove a scientific hypothesis

Manuscripts which will not be considered include:

bioinformatic analyses without a solid statistical approach
"stand alone" bioinformatic analyses without experimental proof

Editorial Policy Regarding Submissions Focusing on Non-coding RNAs or RNA Modifications

Since epigenetic regulation and associated aspects of transcription regulation are wide-spread and complex, Epigenetics Communications aims to focus on those aspects of ncRNA-induced epigenetic regulation that concern changes in chromatin organization. As such manuscripts on non-coding RNAs or RNA modifications are only acceptable for the journal when including:

data on the molecular epigenetic regulation of the expression of non-coding RNA (or its modifying enzymes) or
insights on the mechanism of action of the non-coding RNA on the chromatin and/or functioning of the DNA or
insights in mitotic stability of the RNA-induced effect

Editorial Policy Regarding Submissions Focusing on In silico research

Manuscripts reporting on straightforward bioinformatic analyses of publicly accessible databases only, cannot be considered for publication in Epigenetics Communications, unless the manuscript presents:

new, convincingly-described, scientific insights which will impact the field and/or
additional insights into underlying biological mechanisms (“wet-lab” validations) and/or
validations of findings in a replication cohort

Editors-in-Chief

Lucia Altucci, Università degli Studi della Campania, Italy
Marianne Rots, University Medical Center Groningen, Netherlands

Aims and scope

Encompassing the broad spectrum of epigenetics research from basic research to innovations towards therapeutic treatments, Epigenetics Communications is an innovative new, open-access journal devoted to the study of epigenetic principles and mechanisms in basic research settings. In support of open science initiatives, the journal will have a level 4 data policy requiring data be made publically available. The journal is divided into the following sections:

Molecular Epigenetics (Histone Modifications; DNA Methylation; DNA Demethylation)
Nuclear Organization
Mitotic & Meiotic Heritability
Epigenetic Drugs
Epigenetic Technologies
Epigenetic Bioengineering
Network Epigenetics
Computational Epigenomics
Single Cell Epigenetics
Epigenetic Toxicology
Model Organisms (Vertebrates; Invertebrates; Plants; Unicellular systems)

Epigenetics Communications will support the publication of manuscripts that contribute to a further understanding of epigenetic mechanisms that impact functioning of systems and organisms. Submissions describing clinical applications are referred to the sister journal, Clinical Epigenetics.

This new and innovative journal will also act as a forum to showcase and discuss alternative conclusions/interpretations of well-established epigenetic phenomena based on (re-)analyses of published or new data. As such, we welcome 'systematic studies', be it positive (expected) or negative (non-expected) with respect to its outcome.