Fig. 6

HDAC activity and ac-tubulin in Syrian hamster liver. A HDAC activity in SE animals (n = 3) using inhibitors: Entinostat to inhibit class I HDACs, Tubastatin A to inhibit HDAC6, and Vorinostat to inhibit all HDACs, except Sirtuins. B Levels of acetyl-tubulin (n = 4) relative to tubulin measured using Western blot. Measurements were performed on samples obtained from summer euthermic (SE), torpor late (TL), and arousal late (AL). Data represented as mean ± s.e.m. and are relative to the mean of SE. Statistical analysis by Kruskal-Wallis with Dunn’s correction *P < 0.05; **P < 0.01, ****P < 0.0001