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Fig. 1 | Epigenetics Communications

Fig. 1

From: Iron homeostasis pathway DNA methylation trajectories reveal a role for STEAP3 metalloreductase in patient outcomes after aneurysmal subarachnoid hemorrhage

Fig. 1

Overview of study workflow and findings. aSAH, aneurysmal subarachnoid hemorrhage; QC, quality control; GBTA, group-based trajectory analysis; CTH, cell type heterogeneity; CV, cerebral vasospasm; DCI, delayed cerebral ischemia; GOS, Glasgow Outcome Scale; N/n notation refers to the number of participants; M/m notation refers to the number of CpG sites; dashed lines represent CTH-adjusted analyses, which were considered a secondary focus of this study given our search for a clinical biomarker; candidate genes correspond to those shown in Table S1

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