Skip to main content

Table 3 Discovery phase differentially methylated regions with adjusted p values less than 0.05 for each trimester

From: A longitudinal epigenome-wide association study of preeclamptic and normotensive pregnancy

Tri.

Chr.

Start position*

End position*

Gene name

Number of CpGs

Adjusted p value^

1

5

171710114

171710573

UBTD2

3

4.31 × 10−3

10

27793008

27793165

RAB18

5

8.26 × 10−7

15

75018774

75019302

CYP1A1

10

3.91 × 10−3

2

2

64067521

64067760

UGP2

3

3.28 × 10−2

10

51572216

51572718

NCOA4

8

9.87 × 10−4

19

59066476

59066632

CHMP2A

7

2.17 × 10−2

3

6

111902385

111902611

TRAF3IP2-AS1; TRAF3IP2

2**

5.53 × 10−4

14

35761327

35761551

PSMA6

5

7.48 × 10−3

17

80560593

80561084

FOXK2

4

1.27 × 10−2

  1. Table ordered by trimester, chromosome, and position
  2. Chr. chromosome, Tri. trimester
  3. *Position based on Human Genome Build 37 (hg19)
  4. ^Adjusted p values calculated as described in the “Methods and materials” section using the Bonferroni approach by dmrff
  5. **Region consists of both cg218829900 and cg16155413 that were selected for trimester 3 replication