Fig. 1
From: A longitudinal epigenome-wide association study of preeclamptic and normotensive pregnancy
Manhattan and QQ plots for trimesters 1, 2, and 3. A Manhattan plots displaying -log10(p value) on y-axis and chromosome number on x-axis. The red line represents the threshold for genome-wide significance with a p value of 9×10-8; the blue line represents the threshold for suggestive significance with a p value of 1×10-5. B QQ plot with 95% confidence interval displaying observed -log10(p value) on y-axis and expected -log10(p value) on x-axis; the red line represents where the points should fall under the null of no association if the statistical tests are well-calibrated and effects of population substructure and other batch effects are well-controlled for