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Fig. 4 | Epigenetics Communications

Fig. 4

From: Potential DNA methylation biomarkers for the detection of clear cell renal cell carcinoma identified by a whole blood-based epigenome-wide association study

Fig. 4

Receiver operating characteristic (ROC) curve plots for sum of DNAm levels of six ccRCC-associated CpGs. a Sum of DNAm levels of the six CpGs of PCBD2/MTND4P12 in ccRCC patients compared with that of TMM controls in the discovery phase. The area under the curve (AUC) is 0.922 (95% CI: 0.871–0.973). b Sum of DNAm levels of the six CpGs in PCBD2/MTND4P12 in ccRCC patients compared with that of TMM controls in the replication phase. The AUC is 0.871 (95% CI: 0.800–0.941). CI, confidence interval; DNAm, DNA methylation; ccRCC, clear cell renal cell carcinoma; TMM, Tohoku Medical Megabank

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Epigenetics Communications

ISSN: 2730-7034