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Fig. 1 | Epigenetics Communications

Fig. 1

From: Potential DNA methylation biomarkers for the detection of clear cell renal cell carcinoma identified by a whole blood-based epigenome-wide association study

Fig. 1

Study workflow. In the discovery phase, we compared the differences in DNAm levels in blood-derived DNA of 50 ccRCC patients and 50 TMM controls, and identified CpGs with altered DNAm levels associated with ccRCC (left column). To confirm the accuracy of the ccRCC-associated CpGs found in the discovery phase, we compared the difference in DNAm levels between another 48 ccRCC patients and 48 TMM controls in the replication phase (right column). DNAm, DNA methylation; ccRCC, clear cell renal cell carcinoma; TMM, Tohoku Medical Megabank

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Epigenetics Communications

ISSN: 2730-7034