Table 2 Performance of epigenetic clocks as biomarkers of chronological age in the CoDuBu study, south-central Côte d’Ivoire

Mean (SD), age (years)

41.5 (13.1)

47.3 (11.3)

39.6 (12.0)

33.7 (13.8)

49.6 (10.9)

36.6 (14.5)

42.7 (11.8)

34.8 (13.0)

27.2 (15.9)

45.9 (13.4)

Mean (SD), EAD (years)

–

5.8 (7.2)

− 1.9 (6.6)

− 7.8 (7.4)

8.1 (4.8)

–

6.1 (7.3)

− 1.8 (5.6)

− 9.4 (7.4)

9.3 (5.4)

95% limits of EAD agreement (years)

–

− 8.4, 19.9

− 14.8, 11.1

− 22.3, 6.7

− 1.3, 17.6

–

− 8.3, 20.4

− 12.7, 9.1

− 23.8, 5.1

− 1.3, 19.9

Lin’s r_C of EA with chronological age

–

0.74

0.85

0.73

0.75

–

0.76

0.91

0.74

0.75

95% CI of Lin’s r_C ^a

–

0.70, 0.78

0.82, 0.88

0.68, 0.76

0.72, 0.78

–

0.60, 0.87

0.84, 0.95

0.61, 0.83

0.61, 0.85

Lin’s coefficient of bias

–

0.89

0.99

0.85

0.80

–

0.88

0.99

0.83

0.81

Mean (SD), EAA (years)

–

0 (6.3)

0 (6.0)

0 (7.3)

0 (3.9)

–

− 1.0 (5.9)

− 0.9 (5.0)

− 2.0 (7.3)

0.1 (5.7)

Pearson’s r of EA with chronological age

–

0.83

0.86

0.85

0.93

–

0.86

0.92

0.89

0.93

Pearson’s r of EAD with chronological age

–

− 0.50

− 0.41

− 0.18

− 0.59

–

− 0.59

− 0.44

− 0.05

− 0.39

Pearson’s r of EAA with chronological age

–

0.00

0.00

0.00

0.00

–

− 0.05

0.10

0.14

0.21