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Fig. 3 | Epigenetics Communications

Fig. 3

From: Long-term aspirin use and epigenetic mitotic clocks for cancer risk prediction: findings in healthy colon mucosa and recommendations for future epigenetic aging studies

Fig. 3

Aspirin use mitotic clock intrinsic rate difference distributions. Boxplots of the differences (T2 − T1) in mitotic clock age-adjusted intrinsic rate (IR) residuals (from models additionally adjusted for BMI, polyp status, and methylation batch) by aspirin use and colon location for EpiTOC (A), EpiTOC2 (B), and MiAge (C). P values are from Wilcoxon rank sum tests comparing differences (T2 − T1) between non-users and long-term aspirin users. T1, timepoint 1 (baseline). T2, timepoint 2 (10-year follow-up)

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Epigenetics Communications

ISSN: 2730-7034