Replication, polynomial order 002, Fig. 2c |
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Group 3 (high) vs. combined group 1 (low) and group 2 (intermediate) |
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Outcome | OR | 95% CI | pc |
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GOS-3 | 8.190 | 2.51 to 31.85 | 0.0010a |
GOS-12 | 6.257 | 1.85 to 24.53 | 0.0047a |
Death-3 | 2.253 | 1.26 to 4.23 | 0.0080a |
Death-12 | 2.028 | 1.10 to 3.92 | 0.0272b |
- Corresponds to trajectory groups depicted in Fig. 2c; GOS-3, Glasgow Outcome Scale at 3 months (unfavorable = 1–3); GOS-12, Glasgow Outcome Scale at 12 months (unfavorable = 1–3); Death-3, death at 3 months; Death-12, death at 12 months. aSignificant associations (meeting empirical significance level) have been bolded. bSuggestive associations (unadjusted p < 0.05) have been underlined. cEmpirical significance threshold = 0.0241 (calculated based on the minimum of 4 p-values in permutation testing)